Arginine is one of the essential amino acids that your body cannot produce on its own. Also known as L-arginine, this amino acid is a heavy weight as a proven releaser of HGH.
Arginine along with ornithine were tested as growth hormone releasers in a study by Dirk Pearson and Sandy Shaw.
In the study Shaw ingested a dose of 10 grams of arginine every day on an empty stomach. The goal was to produce HGH release and subsequently improve the rate of healing on her broken foot.
In combination with the arginine dose, she added exercise in the form of 3 minute bench press workouts (large muscle group that didn't require her broken foot to be involved). Shaw reported a weight loss of 25 lbs of fat with a 5 lb gain of muscle. See Effects Of Growth Hormone.
It appears that arginine stimulates HGH release by blocking a known growth hormone inhibitor - somatostatin. Incidentally, somatostatin production increases as we get older which contributes to less and less HGH release as we age.
Arginine converts to another substance - nitric oxide - which is known to improve blood vessel elasticity. Nitric oxide production can lead to better cardiovascular health and even better erections. Here's how to boost nitric oxide with supplements.
Ornithine can be created by your own body, so it's a nonessential amino acid. Ornithine was used in the Shaw and Pearson study and shown to be two times as effective at releasing HGH as arginine.
The Shaw and Pearson findings were the result of ingesting 2 1/2 to 5 grams of ornithine each night prior to bed on an empty stomach. 5 grams to 10 grams of arginine was taken in combination with the ornithine.
Citrulline may be more effective than arginine at boosting HGH. Citrulline actually metabolizes into arginine. Studies have shown that supplementing with both citrulline and arginine may be more effective than arginine alone.
Our bodies use more glutamine than any other amino acid. Glutamine prevents muscle wasting as associated with times of stress.
High glutamine levels have also been associated with better general health. In one study, for example, high glutamine levels resulted in lower blood pressure, fewer illnesses, lower cholesterol, and maintenance of ideal weight.
Thomas Welbourne showed that a 2 gram dose of glutamine could raise HGH levels in a subject group of men ages 32 to 64.
It's been shown that glutamine can have greater effect alone than the combined effect of arginine, ornithine, and lysine. However, more evidence shows greater effect from stacking amino acids.
Lysine is also an essential amino acid and has been shown to increase HGH even at small doses.
Interesting results from studies with lysine - evidence that growth hormone release may have increased thymic hormone secretion in older animals and humans, resulting in a potential reversal of age-related immune deficiency.
Also, a study at the Mayo Clinic showed lysine at small doses could reduce the recurrence of herpes simplex infections.
Take lysine in combination with other amino acids mentioned earlier, for best results. See Stacking Amino Acids.
OKG - Ornithine Alpha-Ketoglutarate
Although OKG is not specifically an amino acid, it is ornithine bound to alpha-ketoglutarate. Alpha-ketogluterate is a precursor to glutamine.
Studies from France show it to boost growth hormone and help with body tissue rebuilding
Glycine, a nonessential amino acid, is sometimes overlooked as a natural HGH releaser. However, studies have shown large increases of HGH in the blood after supplementing with glycine.